Fibromyalgia syndrome is a type of rheumatism, characterized by diffuse muscle pain, often accompanied by a variety of non-specific symptoms; a typical situation is that the patient has tenderness in certain specific parts of the body and does not require a specific laboratory or disease. Physical examination to help diagnosis.
Patients with fibromyalgia syndrome may have a previous history of physical or mental trauma. The most prominent symptom of fibromyalgia syndrome is diffuse pain throughout the body, lasting for more than 3 months, and some other clinical manifestations, including sleep disturbance, physical stiffness, fatigue, and cognitive dysfunction. Fibromyalgia syndrome is difficult to treat and is currently an incurable chronic pain disease.
1. Central nervous system sensitization
Central nervous system sensitization is one of the main causes of fibromyalgia syndrome. Long-term chronic pain can lead to "central sensitization", which is manifested in the elevation of serotonin (5-HT) and substance P in the cerebrospinal fluid of the patient. In addition, functional MRI technology also shows that the brain is associated with pain in patients with fibromyalgia. Related regional functional activities are enhanced.
2. Immune disorders
Some studies have reported the appearance of anti-thyroid antibodies in the serum of patients, and the levels of interleukin (IL)-1, interleukin-6 (IL-6) and tumor necrosis factor in the serum of some patients are elevated.
Some people think that FS is related to infection, especially Epstein-Barr virus, parvovirus, Burgdorferi spirochetes infection.
The prevalence of first-degree relatives of fibromyalgia patients has increased significantly, suggesting that genetics play a certain role in pathogenesis.
Fibromyalgia syndrome is an idiopathic disease. Its pathophysiology is still unknown. Therefore, treatment is difficult and requires the cooperation of doctors from multiple disciplines. Current treatments are mainly focused on improving sleep status and reducing the sensitivity of pain receptors.
Chinese medicine treatment
Fibromyalgia syndrome belongs to the category of arthralgia of traditional Chinese medicine. Traditional Chinese medicine treatment is implemented to soothe the nerves and nourish the blood. To dredge the tendons and collaterals, invigorate blood circulation to remove blood stasis, promote Qi and relieve pain, so as to relieve the pain and sleep disturbance of the patient.
Tang Sumin, Liu Enlun, Wang Zhiwen. Gua Sha in the treatment of fibromyalgia syndrome. "Sichuan Traditional Chinese Medicine", 2008
Jiang Zhenya, Li Changdu, Qiu Ling, etc. Combination of acupuncture and cupping medicine in the treatment of fibromyalgia syndrome: a multicenter randomized controlled study. "CNKI; WanFang", 2010
Qian Yadong, Zhu Jun. Analysis of 32 cases of fibromyalgia syndrome misdiagnosed as angina pectoris. "CNKI", 2001
Song Caixia, Gao Yuan. Chaihu Shugan Powder for 48 cases of fibromyalgia syndrome. "CNKI", 2013
Gao Yuzhong. Discussion on TCM classification and treatment of fibromyalgia syndrome. "The 4th National Conference on Integrated Traditional Chinese and Western Medicine on Rheumatism", 2000