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High FSH

High follicle-stimulating hormone is seen in testicular seminoma, Kranfelter syndrome, Turner syndrome, primary amenorrhea, congenital ovarian hypoplasia, after treatment with corticosteroids, primary reproductive function Hypothyroidism, ovarian obesity, early hyperpituitary hyperfunction, giant cell degenerative lung cancer, etc.

Follicle-stimulating hormone (FSH), also known as a follicle-stimulating hormone, is secreted by the pituitary gland. In men, its function is to promote the maturation of testicular seminiferous tubules and the production of sperm; in women, the function of FSH is to promote the development and maturation of follicles. And cooperative luteinizing hormone (LH) promotes the secretion of estrogen and ovulation in mature follicles and participates in the formation of normal menstruation. Its production is controlled by hypothalamic gonadotropin releasing hormone, and at the same time by the feedback regulation of ovarian estrogen (E2). FSH plays a decisive role in the sexual and reproductive functions of men and women.

Through the measurement of FSH, we can understand the secretory function of the pituitary, and indirectly understand the functional status of the hypothalamus and ovary. This is very helpful for the differential diagnosis of pituitary or hypothalamic amenorrhea.

Clinical significance

Follicle-stimulating hormone is abbreviated as FSH in modern medicine. It is a substance secreted by the pituitary gland, which determines the development and maturity of human sperm and eggs, and plays a very important role in reproductive function.

In the process of diagnosing female infertility diseases, it is usually necessary to perform multiple medical tests on women of childbearing age. Follicle-stimulating hormone is one of the contents of endocrine tests. This hormone can promote the development and maturation of follicles, and It can promote ovulation and carry out the detection of follicle-stimulating hormone, which has important clinical significance for the treatment of infertility. The function of this test is to help doctors understand whether the secretory function of the pituitary gland in infertile patients is normal and to indirectly grasp whether the function of the hypothalamus and ovary is abnormal, so as to make accurate judgments about the cause of infertility.

If the level of FSH increases, it indicates that women's ovarian function is poor, and may have symptoms such as ovarian hypoplasia, primary amenorrhea, and pituitary precocious puberty. If the FSH level is lower than the normal value, you may suffer from diseases such as polycystic ovary syndrome. Long-term use of contraceptives and excessive use of sex hormones may also cause low FSH levels.


Lei Xueqin, Chen Hong, Yuan Zhifa, et al. Study on the Marking of Bovine Twin Traits by SNP of Follicle Stimulating Hormone Receptor Gene "WanFang", 2002

Yang Jianhua. Follicle-stimulating hormone and testicular spermatogenesis (an analysis of 100 cases). "CNKI", 2001

Cai Pinjun, Huang Wenling, Jin Zhe, Li Ling, etc. The effect of the method of invigorating the kidney and regulating the liver on the expression of ovarian follicle-stimulating hormone receptor mRNA in autoimmune premature ovarian failure mice. "CNKI; WanFang", 2010

Chen Bin, Fan Yuping, Wang Hongxiang, Hu Kai, etc. The relationship between serum follicle-stimulating hormone levels before varicocele surgery and the improvement of postoperative semen parameters. "CNKI; WanFang", 2009

Fan Zhonglin, Li Haiping, Geng Cuizhi, etc. Changes in serum estradiol and follicle-stimulating hormone levels after breast cancer treated with tamoxifen. 2012



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