<<< Back

Induction of labor

Induction of labor means that after 12 weeks of pregnancy, due to maternal or fetal reasons, it is necessary to artificially induce uterine contractions to terminate the pregnancy. According to the gestational week at the time of labor induction, it can be divided into mid-term labor induction (14-28 weeks) and late-term pregnancy induction (after 28 weeks).

Preparation before induction

The success of labor induction is related to various factors. Cervical maturity is an important factor in determining the success of labor induction. Immature cervix, induction of labor is often not easy to succeed. Most people with a mature cervix can give birth vaginally.

1. Cervical score

In 1964, Bishop developed a scoring system to determine whether pregnant women were suitable for selective induction of labor. At present, the commonly accepted method for estimating cervical maturity is the Bishop score. He believes that a score  of 7 points indicate cervical maturity. The higher the score, the more mature, the easier it is to induce labor. If the score is below 6 points, cervical ripening should be promoted.

2. Methods to promote cervical ripening

The cervix is mainly composed of epithelium, smooth muscle, hoof tissue, glands and stroma. Cervical maturity is not necessarily proportional to the gestational age, but is related to the biological changes of the cervical tissue. After pregnancy, cervical tissue changes, which are obvious as the pregnancy progresses, and reach the peak during childbirth. The typical manifestations are: collagen fibers are significantly reduced and loose and meshed; blood vessels are engorged and hyperemic; white blood cells accumulate and adhere to the wall, and a large number of interstitials appear Of white blood cells and fibroblasts. Cervical maturation may be the result of a variety of hormones, such as estrogen, progesterone, relaxin and prostaglandin.

Methods of Induction of Labor Voice

The ideal method for promoting cervical ripening is similar to its natural ripening process. It does not cause excessive uterine contraction, does not affect uterine blood flow, and does not endanger the safety of the fetus and mother. There are many ways to promote cervical ripening, but there is no perfect and very effective method yet. At present, the commonly used methods are divided into two categories: non-drug and drug-based:

1. Non-pharmaceutical methods

Artificial membrane peeling (basically not used); Artificial membrane rupture (not effective when used alone); Water bladder or Foley catheter (unconventional use); Hygroscopic expansion or Lamicel stick (used sparingly); Nipple irritation ( Not commonly used); Acupuncture therapy (basically not used).

2. Drug therapy

Oxytocin, low-dose and low-concentration intravenous drip; Prostaglandin PGE2 (conventional use); PGE2 gel intracervical administration (rarely used); PGE2 vaginal controlled-release tablets-Probexen (commonly used); Misoprost Alcohol (unconventional use); vaginal misoprostol; carbogestation suppository (basically not used); mifepristone (not used for late induction of labor).


Wang Chenhong. The application of mifepristone in labor induction. "Chinese Journal of Practical Gynecology and Obstetrics", 2002

Liu Jie, Wang Jingyun. Induction and induction of labor in scarred uterine pregnancy. 2002

Wang Dezhi. The methods and precautions of oxytocin inducing labor and inducing labor. "Chinese Journal of Practical Gynecology and Obstetrics", 2002

Dai Zhongying. Application of prostaglandins in the induction of labor in term pregnancy. "CNKI", 1999

Du Xiuying, Dai Mingyu. Application of misoprostol in the induction of labor in term pregnancy. "Chinese Journal of Practical Gynecology and Obstetrics", 2001

引产 引產


<<< Back